Professor

B.S., U Wales 1963, Ph.D. 1967

E-Mail: baynec@bcc.orst.edu, Phone: 541-737-5352, FAX: 541-737-0501, Address: Department of Zoology, Oregon State University, Corvallis, Oregon 97331-2914.

As a comparative immunologist with interests in the evolution of immunity, my interests focus on gaining a deeper understanding of innate immune systems and their modulation. In my lab, research exploits two models: the rainbow trout in which we study inflammatory components of the acute phase response, and effects of stress on innate immunity, and molluscan schistosomiasis, in which we investigate the mechanisms that determine susceptibility and resistance in this host-parasite system.

 I teach a “Scientific Skills” seminar for new graduate students, Human Anatomy & Physiology, and Scientific Communication for Biologists (Z 414). I also offer seminars and participate in areas of courses dealing with immunological aspects of cell biology and physiology. I serve as academic advisor to both undergraduates and graduate students.

 Persons who have completed graduate degrees with me are in both research (Parke-Davis) and sales (Molecular Devices Corp) in the biotech industry, while others teach (Florida International University) and do research (University of Florida) in universities.

 Beyond the OSU campus, I am immediate Past-President of the International Society for Developmental and Comparative Immunology. I also serve my profession through providing critical appraisals of research proposals submitted to funding organizations, and manuscripts submitted for publication in journals.

Further details?

http://www.orst.edu/dept/cgrb/faculty/bayne/index.html

http://www.ehsc.orst.edu/investigators/bayne.htm

Representative Recent Publications: 

 Gerwick, L., Reynolds, W.S. and Bayne, C.J. 2000. A precerebellin-like protein is part of the acute phase response in rainbow trout. Developmental and Comparative Immunology. 24: 597-607.

Hahn, U.K., Bender, R.C. and Bayne, C.J. 2000. Production of reactive oxygen species by hemocytes of Biomphalaria glabrata: carbohydrate-specific stimulation. Developmental and Comparative Immunology.24: 531-541.

Hahn, U.K., Bender, R.C. and Bayne, C.J. 2001. Killing of Schistosoma mansoni sporocysts by hemocytes from resistant Biomphalaria glabrata: role of reactive oxygen species. Journal of Parasitology. 87:  292-299.

Bayne, C.J., Gerwick, L., Kazuhiro Fujiki, Miki Nakao and Tomoki Yano. 2001. Immune-relevant (including acute phase) genes identified in the livers of rainbow trout, Oncorhynchus mykiss, by suppression subtractive hybridization. Developmental and Comparative Immunology. 25:205-217.

Loker, E.S. and Bayne, C.J. 2001. Molecular Studies of the Molluscan Response to Digenean Infection. In: Phylogenetic perspectives on the vertebrate immune system. pp. 209-222. Beck, G, Sugumaran and Cooper, E.L. (eds.). Kluwer. In press.

Hahn, U.K, Bender, R.C. and Bayne, C.J. 2001. The role of nitric oxide in killing of Schistosoma mansoni sporocysts by hemocytes from resistant Biomphalaria glabrata. Journal of Parasitology. In press.

Fujiki, K., Bayne, C.J., Shin, D.-H., Nakao, M. and Yano, T. 2001. Molecular cloning of carp (Cyprinus carpio) C-type lectin and pentraxin by use of suppression subtractive hybridisation. Fish and Shellfish Immunology. In press.

Bayne, C.J. and Gerwick, L. 2001. The acute phase response and innate immunity in fish. Invited chapter in Developmental and Comparative Immunology. In press.

Bayne, C.J., Hahn, U.K. and Bender, R.C. 2001. Mechanisms of molluscan host resistance and parasite escapes. Invited Chapter In: Flukes and Snails. Rollinson, David (ed). In press.