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Dr. John E. Morris

Professor (Emeritus)

B.S., Stanford U, 1958; M.S., U Hawaii, 1960; Ph.D., U California, Los Angeles, 1966

 


E-Mail:  morrisj@science.oregonstate.edu, Phone: 541-737-3705, FAX: 541-737-0501, Address: Department of Zoology, Oregon State University, Corvallis, Oregon 97331-2914.

I continue to have a broad interest in cellular and developmental biology, with a particular interest in the cell-to-cell and cell-to-matrix interactions in the formation of tissues and organs. I taught Embryology and Development (Z 425/525), Histology (Z 461/561), and Vertebrate Physiology (Z 431/531). I also directed students working on cellular and developmental problems.

Research in my laboratory focused on two major systems. The first of these is organogenesis in embryonic chicken, particularly retina and limb. Published studies in this system have ranged from the regulation of hormonal response by cellular organization, to biochemical characterization of the proteoglycans, to the influence of glycosaminoglycans and other linear polymers on cell adhesion and migration.

The other major system is the initial attachment of mouse embryos to the uterine surface at the time of implantation. We have a particular interest in the mechanism by which steroids control the interactions between blastocyst and uterine epithelium and in understanding the influence of steroids on uterine epithelial cell-cell adhesion and extracellular matrix macromolecules. Publications include the demonstration of a hanging drop system for studying embryo development and blastocyst-uterine epithelium interaction and the investigation of changes in cell surface charge, extracellular matrix, and cadherins during implantation and the estrous cycle. in mice.

Now that I have your attention, here's a plug for the web site for one of my interests: Chamber Music Corvallis, www.violins. org.This organization promotes and sponsors chamber music concerts at the LaSells-Stewart Center on the OSU campus. Check the web site for concert and ticket information.


Representative  Publications:


Potter SW, Gaza G and Morris JE., 1996. Estradiol Induces E-Cadherin Degradation in Mouse Uterine Epithelium During the Estrous Cycle and Early Pregnancy. J. Cell. Physiol., 169:1-14.
Morris JE, Gaza G and Potter SW,1994, Specific stimulation of basal lamina heparan sulfate proteoglycan in mouse uterine epithelium by Matrigel and by transforming growth factor-beta 1. In Vitro Cell Dev Biol Anim. 30A:120-8.
Chai, L and Morris, JE, 1994, Distribution of heparan sulfate proteoglycans in embryonic chicken neural retina and isolated inner limiting membrane. Curr Eye Res.13:669-77.
Astrahantseff KN, and Morris JE, 1994. Estradiol-17 beta stimulates proliferation of uterine epithelial cells cultured with stromal cells but not cultured separately. In Vitro Cell Dev Biol Anim. 30A:769-76.
Morris JE., 1993. Proteoglycans and the modulation of cell adhesion by steric exclusion. Devel. Dynamics 196:246-251. A review.